Genotoxic effects induced by zearalenone in a human embryonic kidney cell line
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چکیده
منابع مشابه
Lipocalin2 Protects Human Embryonic Kidney Cells against Cisplatin–Induced Genotoxicity
Cisplatin is one of the most useful chemotherapeutics which performs its cytotoxic effectvia accumulation of platinum resulting in oxidative stress, and destruction of cell DNA. Thiscould probably cause secondary cancers in healthy tissues. Lipocalin2 (Lcn2) is a protein whichits expression is increased in oxidative stresses. Therefore, the present study was performedto evaluate the protective ...
متن کاملThe Genotoxic and Cytotoxic Effects of Bisphenol-A (BPA) in MCF-7 Cell Line and Amniocytes
Bisphenol-A (BPA) is an industrial xenoestrogen used widely in our living environment. Recently, several studies suggested that BPA has destructive effects on DNA and chromosomes in normal body cells via estrogen receptors (ER). Therefore, BPA could be considered as an important mediator in many diseases such as cancer. However, there are still many controversial issues which need clarification...
متن کاملLipocalin2 Protects Human Embryonic Kidney Cells against Cisplatin–Induced Genotoxicity
Cisplatin is one of the most useful chemotherapeutics which performs its cytotoxic effectvia accumulation of platinum resulting in oxidative stress, and destruction of cell DNA. Thiscould probably cause secondary cancers in healthy tissues. Lipocalin2 (Lcn2) is a protein whichits expression is increased in oxidative stresses. Therefore, the present study was performedto evaluate the protective ...
متن کاملAntioxidant Effects of Pinus Eldarica Extracts Against Cisplatin-Induced Cytotoxicity in Human Hepatoma (Hepg2) Cell Line
Background: Cisplatin has cytotoxic effects through free radical generation. Reports indicate that various members of Pinaceae family may have antioxidant properties. In this study we investigated the cytoprotective effects of needle volatile oil and bark extract of Pinus eldarica in hepatoma G2 (HepG2) cell line. Methods: Using the maceration technique, we obtained the ethanolic extract of ...
متن کاملproduction of biosimilar human like erythropoietin (epo) by human embryonic kidney (hek293) cell line, its advantages and disadvantages to cho cell line
background: erythropoietin (epo) is a glycoprotein hormone function to regulate the production of red blood cells. deficiency of epo is known to cause anemia in chronically infected renal patients and they require regular blood transfusion. availability of recombinant epo has eliminated the need for blood transfusion and now it is extensively used for the treatment of anemia. glycosylation of e...
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ژورنال
عنوان ژورنال: Mutation Research/Genetic Toxicology and Environmental Mutagenesis
سال: 2013
ISSN: 1383-5718
DOI: 10.1016/j.mrgentox.2013.04.009